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Image Search Results
Journal: International Journal of Molecular Medicine
Article Title: Apremilast prevents IL-17-induced cellular senescence in ATDC5 chondrocytes mediated by SIRT1
doi: 10.3892/ijmm.2021.4845
Figure Lengend Snippet: Apremilast prevents IL-17-induced production of ROS in mouse ATDC5 chondrocytes. Cells were treated with IL-17 (10 ng/ml) in the presence or absence of apremilast (0.5 and 1 µ M) for 24 h. Production of ROS was measured using DCFH-DA staining (magnification, ×10). #### P<0.0001 vs. the vehicle control group; ** P<0.01 and *** P<0.001 vs. the IL-17 group. ROS, reactive oxygen species; IL, interleukin; DCFH-DA, 2,7-dichlorodihy-drofluorescein diacetate.
Article Snippet:
Techniques: Staining, Control
Journal: International Journal of Molecular Medicine
Article Title: Apremilast prevents IL-17-induced cellular senescence in ATDC5 chondrocytes mediated by SIRT1
doi: 10.3892/ijmm.2021.4845
Figure Lengend Snippet: Graphical representation of the underlying mechanism, whereby apremilast prevents IL-17-induced cellular senescence in ATDC5 chondrocytes. IL, interleukin; ROS, reactive oxygen species; SIRT1, sirtuin 1; MCP-1, monocyte chemoattractant protein-1; PAI-1, plasminogen activator inhibitor-1.
Article Snippet:
Techniques: